Overexpression of p53 activated by small activating RNA suppresses the growth of human prostate cancer cells

Previous research has reported that a particular double-stranded RNA, named dsP53-285, has the capacity to induce expression of the tumor suppressor gene TP53 in chimpanzee cells by targeting its promoter. Usually, it is the wild-type p53 protein, rather than mutants, which exhibits potent cancer-in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Onco Targets Ther
Prif Awduron: Ge, Qiangqiang, Wang, Chenghe, Ruan, Yajun, Chen, Zhong, Liu, Jihong, Ye, Zhangqun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2016
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712973/
https://ncbi.nlm.nih.gov/pubmed/26811691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S96710
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