Structural forms of the human amylase locus and their relationships to SNPs, haplotypes, and obesity

Hundreds of genes reside in structurally complex, poorly understood regions of the human genome(1-3). One such region contains the three amylase genes (AMY2B, AMY2A, and AMY1) responsible for digesting starch into sugar. The copy number of AMY1 is reported to be the genome’s largest influence on obe...

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Foilsithe in:Nat Genet
Main Authors: Usher, Christina L, Handsaker, Robert E, Esko, Tõnu, Tuke, Marcus A, Weedon, Michael N, Hastie, Alex R, Cao, Han, Moon, Jennifer E, Kashin, Seva, Fuchsberger, Christian, Metspalu, Andres, Pato, Carlos N, Pato, Michele T, McCarthy, Mark I, Boehnke, Michael, Altshuler, David M, Frayling, Timothy M, Hirschhorn, Joel N, McCarroll, Steven A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712930/
https://ncbi.nlm.nih.gov/pubmed/26098870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3340
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