Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification

Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from a single couple. Compared with numerous...

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Detaylı Bibliyografya
Yayımlandı:Development
Asıl Yazarlar: Zdravkovic, Tamara, Nazor, Kristopher L., Larocque, Nicholas, Gormley, Matthew, Donne, Matthew, Hunkapillar, Nathan, Giritharan, Gnanaratnam, Bernstein, Harold S., Wei, Grace, Hebrok, Matthias, Zeng, Xianmin, Genbacev, Olga, Mattis, Aras, McMaster, Michael T., Krtolica, Ana, Valbuena, Diana, Simón, Carlos, Laurent, Louise C., Loring, Jeanne F., Fisher, Susan J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2015
Konular:
Stem Cells and Regeneration
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712832/
https://ncbi.nlm.nih.gov/pubmed/26483210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.122846
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