Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification

Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from a single couple. Compared with numerous...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Development
Prif Awduron: Zdravkovic, Tamara, Nazor, Kristopher L., Larocque, Nicholas, Gormley, Matthew, Donne, Matthew, Hunkapillar, Nathan, Giritharan, Gnanaratnam, Bernstein, Harold S., Wei, Grace, Hebrok, Matthias, Zeng, Xianmin, Genbacev, Olga, Mattis, Aras, McMaster, Michael T., Krtolica, Ana, Valbuena, Diana, Simón, Carlos, Laurent, Louise C., Loring, Jeanne F., Fisher, Susan J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Company of Biologists 2015
Pynciau:
Stem Cells and Regeneration
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712832/
https://ncbi.nlm.nih.gov/pubmed/26483210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.122846
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