Human stem cells from single blastomeres reveal pathways of embryonic or trophoblast fate specification

Mechanisms of initial cell fate decisions differ among species. To gain insights into lineage allocation in humans, we derived ten human embryonic stem cell lines (designated UCSFB1-10) from single blastomeres of four 8-cell embryos and one 12-cell embryo from a single couple. Compared with numerous...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Zdravkovic, Tamara, Nazor, Kristopher L., Larocque, Nicholas, Gormley, Matthew, Donne, Matthew, Hunkapillar, Nathan, Giritharan, Gnanaratnam, Bernstein, Harold S., Wei, Grace, Hebrok, Matthias, Zeng, Xianmin, Genbacev, Olga, Mattis, Aras, McMaster, Michael T., Krtolica, Ana, Valbuena, Diana, Simón, Carlos, Laurent, Louise C., Loring, Jeanne F., Fisher, Susan J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Stem Cells and Regeneration
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712832/
https://ncbi.nlm.nih.gov/pubmed/26483210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.122846
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