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Sqstm1–GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells

Sqstm1 serves as a signaling hub and receptor for selective autophagy. Consequently, dysregulation of Sqstm1 causes imbalances in signaling pathways and disrupts proteostasis, thereby contributing to the development of human diseases. Environmental stresses influence the level of Sqstm1 by altering...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Eino, Atsushi, Kageyama, Shun, Uemura, Takefumi, Annoh, Hiromichi, Saito, Tetsuya, Narita, Ichiei, Waguri, Satoshi, Komatsu, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712822/
https://ncbi.nlm.nih.gov/pubmed/26483381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.180174
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