A carregar...
Spatial control of Shoc2-scaffold-mediated ERK1/2 signaling requires remodeling activity of the ATPase PSMC5
The scaffold protein Shoc2 accelerates activity of the ERK1 and ERK2 (ERK1/2, also known as MAPK3 and MAPK1) pathway. Mutations in Shoc2 result in Noonan-like RASopathy, a developmental disorder with a wide spectrum of symptoms. The amplitude of the ERK1/2 signals transduced through the complex is f...
Na minha lista:
| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712819/ https://ncbi.nlm.nih.gov/pubmed/26519477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.177543 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|