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p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK–myosin-II pathway

Tubulogenesis is fundamental to the development of many epithelial organs. Although lumen formation in cysts has received considerable attention, less is known about lumenogenesis in tubes. Here, we utilized tubulogenesis induced by hepatocyte growth factor (HGF) in MDCK cells, which form tubes encl...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Cell Sci
Main Authors: Kim, Minji, M. Shewan, Annette, Ewald, Andrew J., Werb, Zena, Mostov, Keith E.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Company of Biologists 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712812/
https://ncbi.nlm.nih.gov/pubmed/26483385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172361
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