Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks

Mutations in the cytoskeletal linker protein plectin result in multisystemic diseases affecting skin and muscle with indications of additional vascular system involvement. To study the mechanisms underlying vascular disorders, we established plectin-deficient endothelial cell and mouse models. We sh...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Osmanagic-Myers, Selma, Rus, Stefanie, Wolfram, Michael, Brunner, Daniela, Goldmann, Wolfgang H., Bonakdar, Navid, Fischer, Irmgard, Reipert, Siegfried, Zuzuarregui, Aurora, Walko, Gernot, Wiche, Gerhard
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712781/
https://ncbi.nlm.nih.gov/pubmed/26519478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172056
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