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Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks

Mutations in the cytoskeletal linker protein plectin result in multisystemic diseases affecting skin and muscle with indications of additional vascular system involvement. To study the mechanisms underlying vascular disorders, we established plectin-deficient endothelial cell and mouse models. We sh...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Osmanagic-Myers, Selma, Rus, Stefanie, Wolfram, Michael, Brunner, Daniela, Goldmann, Wolfgang H., Bonakdar, Navid, Fischer, Irmgard, Reipert, Siegfried, Zuzuarregui, Aurora, Walko, Gernot, Wiche, Gerhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712781/
https://ncbi.nlm.nih.gov/pubmed/26519478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172056
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