Plectin reinforces vascular integrity by mediating crosstalk between the vimentin and the actin networks

Mutations in the cytoskeletal linker protein plectin result in multisystemic diseases affecting skin and muscle with indications of additional vascular system involvement. To study the mechanisms underlying vascular disorders, we established plectin-deficient endothelial cell and mouse models. We sh...

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Publicat a:J Cell Sci
Autors principals: Osmanagic-Myers, Selma, Rus, Stefanie, Wolfram, Michael, Brunner, Daniela, Goldmann, Wolfgang H., Bonakdar, Navid, Fischer, Irmgard, Reipert, Siegfried, Zuzuarregui, Aurora, Walko, Gernot, Wiche, Gerhard
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712781/
https://ncbi.nlm.nih.gov/pubmed/26519478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.172056
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