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ERAD of proteins containing aberrant transmembrane domains requires ubiquitylation of cytoplasmic lysine residues
Clearance of misfolded proteins from the endoplasmic reticulum (ER) is mediated by the ubiquitin-proteasome system in a process known as ER-associated degradation (ERAD). The mechanisms through which proteins containing aberrant transmembrane domains are degraded by ERAD are poorly understood. To ad...
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| Publicado no: | J Cell Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4712780/ https://ncbi.nlm.nih.gov/pubmed/26446255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.171215 |
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