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Differential analyses for RNA-seq: transcript-level estimates improve gene-level inferences

High-throughput sequencing of cDNA (RNA-seq) is used extensively to characterize the transcriptome of cells. Many transcriptomic studies aim at comparing either abundance levels or the transcriptome composition between given conditions, and as a first step, the sequencing reads must be used as the b...

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Detalhes bibliográficos
Publicado no:F1000Res
Main Authors: Soneson, Charlotte, Love, Michael I., Robinson, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712774/
https://ncbi.nlm.nih.gov/pubmed/26925227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7563.2
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