The dietary flavonoid rhamnetin inhibits both inflammation and excitotoxicity during ethanol withdrawal in rat organotypic hippocampal slice cultures

BACKGROUND: Ethanol causes neurotoxicity via several mechanisms including neuroinflammation (during ethanol exposure), and excitotoxicity (during ethanol withdrawal – EWD). Alpha7 nicotinic acetylcholine receptor (nAChR) selective agonists have the potential to reduce both. The aim of this study was...

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Bibliografiske detaljer
Udgivet i:Alcohol Clin Exp Res
Main Authors: Lutz, Joseph A., Carter, Megan, Fields, Logan, Barron, Susan, Littleton, John M.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712100/
https://ncbi.nlm.nih.gov/pubmed/26577991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12896
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