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An organotypic hippocampal slice culture model of excitotoxic injury induced spontaneous recurrent epileptiform discharges

Stroke is the major cause of acquired epilepsy in the adult population. The mechanisms of ischemia-induced epileptogenesis are not completely understood, but glutamate is associated with both ischemia-induced injury and epileptogenesis. The objective of this study was to develop an in vitro model of...

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Detalhes bibliográficos
Main Authors: Ziobro, Julie M., Deshpande, Laxmikant S., DeLorenzo, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022076/
https://ncbi.nlm.nih.gov/pubmed/21111720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.11.065
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