Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction

BACKGROUND: Nitrates are commonly prescribed to enhance activity tolerance in patients with heart failure and a preserved ejection fraction. We compared the effect of isosorbide mononitrate or placebo on daily activity in such patients. METHODS: In this multicenter, double-blind, crossover study, 11...

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Publicado en:N Engl J Med
Main Authors: Redfield, Margaret M., Anstrom, Kevin J., Levine, James A., Koepp, Gabe A., Borlaug, Barry A., Chen, Horng H., LeWinter, Martin M., Joseph, Susan M., Shah, Sanjiv J., Semigran, Marc J., Felker, G. Michael, Cole, Robert T., Reeves, Gordon R., Tedford, Ryan J., Tang, W.H. Wilson, McNulty, Steven E., Velazquez, Eric J., Shah, Monica R., Braunwald, Eugene
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712067/
https://ncbi.nlm.nih.gov/pubmed/26549714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1510774
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