Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia

Transcriptional deregulation plays a major role in acute myeloid leukemia, and therefore identification of epigenetic modifying enzymes essential for the maintenance of oncogenic transcription programs holds the key to better understanding of the biology and designing effective therapeutic strategie...

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Publicado en:Cancer Cell
Autores principales: Cheung, Ngai, Fung, Tsz Kan, Zeisig, Bernd B., Holmes, Katie, Rane, Jayant K., Mowen, Kerri A., Finn, Michael G., Lenhard, Boris, Chan, Li Chong, So, Chi Wai Eric
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712026/
https://ncbi.nlm.nih.gov/pubmed/26766589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.007
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