Automethylation of Protein Arginine Methyltransferase 8 (PRMT8) Regulates Activity by Impeding S-Adenosylmethionine Sensitivity

Protein arginine methyltransferase (PRMT) 8 is unique among the PRMTs, as it has a highly restricted tissue expression pattern and an N terminus that contains two automethylation sites and a myristoylation site. PRMTs catalyze the transfer of a methyl group from S-adenosylmethionine (AdoMet) to a pe...

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Detalhes bibliográficos
Main Authors: Dillon, Myles B. C., Rust, Heather L., Thompson, Paul R., Mowen, Kerri A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784702/
https://ncbi.nlm.nih.gov/pubmed/23946480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.491092
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