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Contributions of microbiome and mechanical deformation to intestinal bacterial overgrowth and inflammation in a human gut-on-a-chip

A human gut-on-a-chip microdevice was used to coculture multiple commensal microbes in contact with living human intestinal epithelial cells for more than a week in vitro and to analyze how gut microbiome, inflammatory cells, and peristalsis-associated mechanical deformations independently contribut...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Kim, Hyun Jung, Li, Hu, Collins, James J., Ingber, Donald E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711860/
https://ncbi.nlm.nih.gov/pubmed/26668389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522193112
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