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Nuclear deformability and telomere dynamics are regulated by cell geometric constraints

Forces generated by the cytoskeleton can be transmitted to the nucleus and chromatin via physical links on the nuclear envelope and the lamin meshwork. Although the role of these active forces in modulating prestressed nuclear morphology has been well studied, the effect on nuclear and chromatin dyn...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Makhija, Ekta, Jokhun, D. S., Shivashankar, G. V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711833/
https://ncbi.nlm.nih.gov/pubmed/26699462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513189113
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