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Structural dynamics of cisplatin binding to histidine in a protein
The platinum anti-cancer agents cisplatin and carboplatin bind to the histidine 15 residue in the model protein hen egg white lysozyme. By using temperatures either side of the protein glass transition state (∼180 K), several platinum binding modes are seen and show that not all these platinum modes...
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| Publicado no: | Struct Dyn |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Crystallographic Association
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711607/ https://ncbi.nlm.nih.gov/pubmed/26798779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4883975 |
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