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Phenylephrine preconditioning in embryonic heart H9c2 cells is mediated by up-regulation of SUR2B/Kir6.2: A first evidence for functional role of SUR2B in sarcolemmal K(ATP) channels and cardioprotection
ATP-sensitive K(+) (K(ATP)) channels were originally described in cardiomyocytes, where physiological levels of intracellular ATP keep them in a closed state. Structurally, these channels are composed of pore-forming inward rectifier, Kir6.1 or Kir6.2, and a regulatory, ATP-binding subunit, SUR1, SU...
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| Veröffentlicht in: | Int J Biochem Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711337/ https://ncbi.nlm.nih.gov/pubmed/26556311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2015.10.029 |
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