The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma

BACKGROUND: In spite of progress in diagnostics and treatment of Hepatocellular Carcinoma (HCC), its prognosis remains poor, and improved treatment strategies for HCC require detailed understanding of the underlying mechanism. In this investigation we studied the role of Up-frameshift 1 (UPF1) in th...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Chang, Lei, Li, Cuicui, Guo, Tao, Wang, Haitao, Ma, Weijie, Yuan, Yufeng, Liu, Quanyan, Ye, Qifa, Liu, Zhisu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711019/
https://ncbi.nlm.nih.gov/pubmed/26759305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0286-2
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