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The human RNA surveillance factor UPF1 regulates tumorigenesis by targeting Smad7 in hepatocellular carcinoma

BACKGROUND: In spite of progress in diagnostics and treatment of Hepatocellular Carcinoma (HCC), its prognosis remains poor, and improved treatment strategies for HCC require detailed understanding of the underlying mechanism. In this investigation we studied the role of Up-frameshift 1 (UPF1) in th...

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Bibliografiska uppgifter
I publikationen:J Exp Clin Cancer Res
Huvudupphovsmän: Chang, Lei, Li, Cuicui, Guo, Tao, Wang, Haitao, Ma, Weijie, Yuan, Yufeng, Liu, Quanyan, Ye, Qifa, Liu, Zhisu
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711019/
https://ncbi.nlm.nih.gov/pubmed/26759305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0286-2
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