The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster

Ataxin-3 is a deubiquitinase and polyglutamine (polyQ) disease protein with a protective role in Drosophila melanogaster models of neurodegeneration. In the fruit fly, wild-type ataxin-3 suppresses toxicity from several polyQ disease proteins, including a pathogenic version of itself that causes spi...

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Gepubliceerd in:Neurobiol Dis
Hoofdauteurs: Tsou, Wei-Ling, Ouyang, Michelle, Hosking, Ryan R., Sutton, Joanna R., Blount, Jessica R., Burr, Aaron A., Todi, Sokol V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710962/
https://ncbi.nlm.nih.gov/pubmed/26007638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.05.010
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