Fatty acid nitroalkenes induce resistance to ischemic cardiac injury by modulating mitochondrial respiration at complex II

Nitro-fatty acids (NO(2)-FA) are metabolic and inflammatory-derived electrophiles that mediate pleiotropic signaling actions. It was hypothesized that NO(2)-FA would impact mitochondrial redox reactions to induce tissue-protective metabolic shifts in cells. Nitro-oleic acid (OA-NO(2)) reversibly inh...

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Publicat a:Redox Biol
Autors principals: Koenitzer, Jeffrey R., Bonacci, Gustavo, Woodcock, Steven R., Chen, Chen-Shan, Cantu-Medellin, Nadiezhda, Kelley, Eric E., Schopfer, Francisco J.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710799/
https://ncbi.nlm.nih.gov/pubmed/26722838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2015.11.002
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