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Tmc1 Point Mutation Affects Ca(2+) Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells

The transduction of sound into electrical signals depends on mechanically sensitive ion channels in the stereociliary bundle. The molecular composition of this mechanoelectrical transducer (MET) channel is not yet known. Transmembrane channel-like protein isoforms 1 (TMC1) and 2 (TMC2) have been pro...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Corns, Laura F., Johnson, Stuart L., Kros, Corné J., Marcotti, Walter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710764/
https://ncbi.nlm.nih.gov/pubmed/26758827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2439-15.2016
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