Novel Cancer-Targeting SPECT/NIRF Dual-modality Imaging Probe (99m)Tc -PC-1007: Synthesis and Biological Evaluation

Synthesis, characterization, in vitro and in vivo biological evaluation of a heptamethine cyanine based dual-mode single-photon emission computed tomography (SPECT)/near infrared fluorescence (NIRF) imaging probe (99m)Tc-PC-1007 is described. (99m)Tc-PC-1007 exhibited preferential accumulation in hu...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Zhang, Yi, Xiao, Li, Popovic, Kosta, Xie, Xiuzhen, Chordia, Mahendra D., Chung, Leland W.K., Williams, Mark B., Yue, Wei, Pan, Dongfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710472/
https://ncbi.nlm.nih.gov/pubmed/24125889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.09.074
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