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Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy

Structural determination of proteins is rather challenging for proteins with molecular masses between 40 - 200 kDa. Considering that more than half of natural proteins have a molecular mass between 40 - 200 kDa(1,2), a robust and high-throughput method with a nanometer resolution capability is neede...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Vis Exp
Egile Nagusiak: Rames, Matthew, Yu, Yadong, Ren, Gang
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MyJove Corporation 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710468/
https://ncbi.nlm.nih.gov/pubmed/25145703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/51087
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