PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection

HIV co-infection is an important risk factor for tuberculosis (TB) providing a powerful model in which to dissect out defective, protective and dysfunctional Mycobacterium tuberculosis (MTB)-specific immune responses. To identify the changes induced by HIV co-infection we compared MTB-specific CD4+...

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Publicat a:PLoS One
Autors principals: Pollock, Katrina M., Montamat-Sicotte, Damien J., Grass, Lisa, Cooke, Graham S., Kapembwa, Moses S., Kon, Onn M., Sampson, Robert D., Taylor, Graham P., Lalvani, Ajit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710462/
https://ncbi.nlm.nih.gov/pubmed/26756579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146905
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