Pooled Amplicon Deep Sequencing of Candidate Plasmodium falciparum Transmission-Blocking Vaccine Antigens

Polymorphisms within Plasmodium falciparum vaccine candidate antigens have the potential to compromise vaccine efficacy. Understanding the allele frequencies of polymorphisms in critical binding regions of antigens can help in the designing of strain-transcendent vaccines. Here, we adopt a pooled de...

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Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Juliano, Jonathan J., Parobek, Christian M., Brazeau, Nicholas F., Ngasala, Billy, Randrianarivelojosia, Milijaona, Lon, Chanthap, Mwandagalirwa, Kashamuka, Tshefu, Antoinette, Dhar, Ravi, Das, Bidyut K., Hoffman, Irving, Martinson, Francis, Mårtensson, Andreas, Saunders, David L., Kumar, Nirbhay, Meshnick, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710419/
https://ncbi.nlm.nih.gov/pubmed/26503281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0571
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