Pooled Amplicon Deep Sequencing of Candidate Plasmodium falciparum Transmission-Blocking Vaccine Antigens

Polymorphisms within Plasmodium falciparum vaccine candidate antigens have the potential to compromise vaccine efficacy. Understanding the allele frequencies of polymorphisms in critical binding regions of antigens can help in the designing of strain-transcendent vaccines. Here, we adopt a pooled de...

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Bibliografiska uppgifter
I publikationen:Am J Trop Med Hyg
Huvudupphovsmän: Juliano, Jonathan J., Parobek, Christian M., Brazeau, Nicholas F., Ngasala, Billy, Randrianarivelojosia, Milijaona, Lon, Chanthap, Mwandagalirwa, Kashamuka, Tshefu, Antoinette, Dhar, Ravi, Das, Bidyut K., Hoffman, Irving, Martinson, Francis, Mårtensson, Andreas, Saunders, David L., Kumar, Nirbhay, Meshnick, Steven R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society of Tropical Medicine and Hygiene 2016
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710419/
https://ncbi.nlm.nih.gov/pubmed/26503281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0571
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