Engineering of stable and fast-folding sequences of model proteins.
The statistical mechanics of protein folding implies that the best-folding proteins are those that have the native conformation as a pronounced energy minimum. We show that this can be obtained by proper selection of protein sequences and suggest a simple practical way to find these sequences. The s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47103/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8346235/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.15.7195 |
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