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The role of functional data in interpreting the effects of genetic variation

Progress in DNA-sequencing technologies has provided a catalogue of millions of DNA variants in the human population, but characterization of the functional effects of these variants has lagged far behind. For example, sequencing of tumor samples is driving an urgent need to classify whether or not...

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Publicat a:Mol Biol Cell
Autors principals: Young, David L., Fields, Stanley
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710221/
https://ncbi.nlm.nih.gov/pubmed/26543197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-03-0153
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