PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis

Poly(ADP-ribose) polymerase 1 (PARP1) interacts genetically with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to suppress early-onset T-lineage lymphomas in the mouse, but the underlying mechanisms have remained unknown. To address this question, we analyzed a series of lymphomas ar...

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Bibliographic Details
Published in:Oncogene
Main Authors: Rybanska, I, Ishaq, O, Chou, J, Prakash, M, Bakhsheshian, J, Huso, DL, Franco, S
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710090/
https://ncbi.nlm.nih.gov/pubmed/22614020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.199
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