Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers

Effective blood–brain tumor barrier penetration and uniform solid tumor distribution can significantly enhance therapeutic delivery to brain tumors. Hydroxyl-functionalized, generation-4 poly(amidoamine) (PAMAM) dendrimers, with their small size, near-neutral surface charge, and the ability to selec...

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Bibliografski detalji
Izdano u:Biomaterials
Glavni autori: Zhang, Fan, Mastorakos, Panagiotis, Mishra, Manoj K., Mangraviti, Antonella, Hwang, Lee, Zhou, Jinyuan, Hanes, Justin, Brem, Henry, Olivi, Alessandro, Tyler, Betty, Kannan, Rangaramanujam M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710089/
https://ncbi.nlm.nih.gov/pubmed/25818456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.053
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