Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers

Effective blood–brain tumor barrier penetration and uniform solid tumor distribution can significantly enhance therapeutic delivery to brain tumors. Hydroxyl-functionalized, generation-4 poly(amidoamine) (PAMAM) dendrimers, with their small size, near-neutral surface charge, and the ability to selec...

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Vydáno v:Biomaterials
Hlavní autoři: Zhang, Fan, Mastorakos, Panagiotis, Mishra, Manoj K., Mangraviti, Antonella, Hwang, Lee, Zhou, Jinyuan, Hanes, Justin, Brem, Henry, Olivi, Alessandro, Tyler, Betty, Kannan, Rangaramanujam M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710089/
https://ncbi.nlm.nih.gov/pubmed/25818456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.02.053
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