Systemic Activation of TLR3-Dependent TRIF Signaling Confers Host Defense against Gram-Negative Bacteria in the Intestine

Recognition of Gram-negative bacteria by toll-like receptor (TLR)4 induces MyD88 and TRIF mediated responses. We have shown that TRIF-dependent responses play an important role in intestinal defense against Gram-negative enteropathogens. In the current study, we examined underlying mechanisms of how...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Ruiz, Jose, Kanagavelu, Saravana, Flores, Claudia, Romero, Laura, Riveron, Reldy, Shih, David Q., Fukata, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710052/
https://ncbi.nlm.nih.gov/pubmed/26793623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2015.00105
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