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A unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses

Both anti-viral and anti-bacterial host defense mechanisms involve TRIF signaling. TRIF provides early clearance of pathogens and coordination of a local inflammatory ensemble through an interferon cascade, while it may trigger organ damage. The multipotentiality of TRIF-mediated immune machinery ma...

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Detalhes bibliográficos
Main Authors: Hyun, Jinhee, Kanagavelu, Saravana, Fukata, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537922/
https://ncbi.nlm.nih.gov/pubmed/23116944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2012.10.011
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