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A unique host defense pathway: TRIF mediates both antiviral and antibacterial immune responses
Both anti-viral and anti-bacterial host defense mechanisms involve TRIF signaling. TRIF provides early clearance of pathogens and coordination of a local inflammatory ensemble through an interferon cascade, while it may trigger organ damage. The multipotentiality of TRIF-mediated immune machinery ma...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3537922/ https://ncbi.nlm.nih.gov/pubmed/23116944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2012.10.011 |
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