Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells

BACKGROUND: Cells of the tumor microenvironment are recognized as important determinants of the tumor biology. The adjacent non-malignant cells can regulate drug responses of the cancer cells by secreted paracrine factors and direct interactions with tumor cells. RESULTS: Human mesenchymal stromal c...

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Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Skolekova, Svetlana, Matuskova, Miroslava, Bohac, Martin, Toro, Lenka, Demkova, Lucia, Gursky, Jan, Kucerova, Lucia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710002/
https://ncbi.nlm.nih.gov/pubmed/26759169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0127-0
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