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Involvement of lysosomal dysfunction in silver nanoparticle-induced cellular damage in A549 human lung alveolar epithelial cells

BACKGROUND: While silver nanoparticles (AgNPs) are widely used in consumer and medical products, the mechanism by which AgNPs cause pulmonary cytotoxicity is not clear. AgNP agglomerates are found in endo-lysosomal structures within the cytoplasm of treated cells. In this study, the functional role...

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Bibliographische Detailangaben
Veröffentlicht in:J Occup Med Toxicol
Hauptverfasser: Miyayama, Takamitsu, Matsuoka, Masato
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709927/
https://ncbi.nlm.nih.gov/pubmed/26759602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12995-016-0090-0
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