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Development and Validation of an HPLC Method for Simultaneous Quantification of Clopidogrel Bisulfate, Its Carboxylic Acid Metabolite, and Atorvastatin in Human Plasma: Application to a Pharmacokinetic Study

A simple, sensitive, and specific reversed phase liquid chromatographic method was developed and validated for simultaneous quantification of clopidogrel, its carboxylic acid metabolite, and atorvastatin in human serum. Plasma samples were deproteinized with acetonitrile and ibuprofen was chosen as...

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Detalhes bibliográficos
Publicado no:J Anal Methods Chem
Main Authors: Croitoru, Octavian, Spiridon, Adela-Maria, Belu, Ionela, Turcu-Ştiolică, Adina, Neamţu, Johny
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709620/
https://ncbi.nlm.nih.gov/pubmed/26839733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/892470
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