Endothelin-1 Predicts Hemodynamically Assessed Pulmonary Arterial Hypertension in HIV Infection

BACKGROUND: HIV infection is an independent risk factor for PAH, but the underlying pathogenesis remains unclear. ET-1 is a robust vasoconstrictor and key mediator of pulmonary vascular homeostasis. Higher levels of ET-1 predict disease severity and mortality in other forms of PAH, and endothelin re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Parikh, Rushi V., Ma, Yifei, Scherzer, Rebecca, Heringer, Amanda S., Macgregor, John S., Martin, Jeffrey N., Deeks, Steven G., Ganz, Peter, Hsue, Priscilla Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709102/
https://ncbi.nlm.nih.gov/pubmed/26752193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146355
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