AB198. Nodal regulates the differentiation of iPS cells to male germ cells via Smad2/3, Oct4 and Foxh1 activation

OBJECTIVE: The differentiation of male germ cells from iPS cells provides an ideal model for unveiling molecular mechanisms of spermatogenesis. Nodal could promote proliferation of mouse spermatogonial stem/progenitor cells via Smad2/3 and oct-4 activation. The objective of this study was to determi...

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Publicado no:Transl Androl Urol
Main Authors: Yang, Shi, Tian, Ruhui, Wang, Junlong, Zhu, Zijue, Li, Peng, Li, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2014
Assuntos:
Abstract Publication Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4708306/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2223-4683.2014.s198
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