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Endothelium-derived hyperpolarization and coronary vasodilation: diverse and integrated roles of epoxyeicosatrienoic acids, hydrogen peroxide and gap junctions

Myocardial perfusion and coronary vascular resistance are regulated by signalling metabolites released from the local myocardium that act either directly on the vascular smooth muscle cells (VSMC) or indirectly via stimulation of the endothelium. A prominent mechanism of vasodilation is endothelium-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Microcirculation
Hauptverfasser: Ellinsworth, David C., Sandow, Shaun L., Shukla, Nilima, Liu, Yanping, Jeremy, Jamie Y., Gutterman, David D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707990/
https://ncbi.nlm.nih.gov/pubmed/26541094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12255
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