Enteric Glia Mediate Neuron Death in Colitis Through Purinergic Pathways That Require Connexin-43 and Nitric Oxide

BACKGROUND & AIMS: The concept of enteric glia as regulators of intestinal homeostasis is slowly gaining acceptance as a central concept in neurogastroenterology. Yet how glia contribute to intestinal disease is still poorly understood. Purines generated during inflammation drive enteric neuron...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Brown, Isola A.M., McClain, Jonathon L., Watson, Ralph E., Patel, Bhavik A., Gulbransen, Brian D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707972/
https://ncbi.nlm.nih.gov/pubmed/26771001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2015.08.007
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