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Hippocampal Injections of Oligomeric Amyloid β-peptide (1–42) Induce Selective Working Memory Deficits and Long-lasting Alterations of ERK Signaling Pathway

Increasing evidence suggests that abnormal brain accumulation of soluble rather than aggregated amyloid-β(1–42) oligomers (Aβo((1–42))) plays a causal role in Alzheimer’s disease (AD). However, as yet, animal’s models of AD based on oligomeric amyloid-β(1–42) injections in the brain have not investi...

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Detaylı Bibliyografya
Yayımlandı:Front Aging Neurosci
Asıl Yazarlar: Faucher, Pierre, Mons, Nicole, Micheau, Jacques, Louis, Caroline, Beracochea, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707555/
https://ncbi.nlm.nih.gov/pubmed/26793098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2015.00245
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