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Evidence for redox sensing by a human cardiac calcium channel

Ion channels are critical to life and respond rapidly to stimuli to evoke physiological responses. Calcium influx into heart muscle occurs through the ion conducting α1C subunit (Ca(v)1.2) of the L-type Ca(2+) channel. Glutathionylation of Ca(v)1.2 results in increased calcium influx and is evident...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Muralidharan, Padmapriya, Cserne Szappanos, Henrietta, Ingley, Evan, Hool, Livia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707475/
https://ncbi.nlm.nih.gov/pubmed/26750869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19067
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