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Ponesimod, a selective S1P1 receptor modulator: a potential treatment for multiple sclerosis and other immune-mediated diseases
The first oral treatment for relapsing multiple sclerosis, the nonselective sphingosine-1-phosphate receptor (S1PR) modulator fingolimod, led to identification of a pivotal role of sphingosine-1-phosphate and one of its five known receptors, S1P(1)R, in regulation of lymphocyte trafficking in multip...
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Publicado no: | Ther Adv Chronic Dis |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
SAGE Publications
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707431/ https://ncbi.nlm.nih.gov/pubmed/26770667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2040622315617354 |
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