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Methionine sulfoxide reductase A is important for lens cell viability and resistance to oxidative stress

Age-related cataract, an opacity of the eye lens, is the leading cause of visual impairment in the elderly, the etiology of which is related to oxidative stress damage. Oxidation of methionine to methionine sulfoxide is a major oxidative stress product that reaches levels as high as 60% in cataract...

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Autors principals: Kantorow, Marc, Hawse, John R., Cowell, Tracy L., Benhamed, Sonia, Pizarro, Gresin O., Reddy, Venkat N., Hejtmancik, J. F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC470730/
https://ncbi.nlm.nih.gov/pubmed/15199188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403532101
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