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Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy

HIV infection profoundly affects many parameters of the immune system and ultimately leads to AIDS, yet which factors are most important for determining resistance, pathology, and response to antiretroviral treatment – and how best to monitor them – remain unclear. We develop a quantitative high-thr...

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Pubblicato in:Front Immunol
Autori principali: Heather, James M., Best, Katharine, Oakes, Theres, Gray, Eleanor R., Roe, Jennifer K., Thomas, Niclas, Friedman, Nir, Noursadeghi, Mahdad, Chain, Benjamin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707277/
https://ncbi.nlm.nih.gov/pubmed/26793190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00644
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