Ethanol Attenuates Histiotrophic Nutrition Pathways and Alters the Intracellular Redox Environment and Thiol Proteome during Rat Organogenesis

Ethanol (EtOH) is a reactive oxygen-generating teratogen involved in the etiology of structural and functional developmental defects. Embryonic nutrition, redox environment, and changes in the thiol proteome following EtOH exposures (1.56.0 mg/ml) were studied in rat whole embryo culture. Glutathion...

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Gepubliceerd in:Toxicol Sci
Hoofdauteurs: Jilek, Joseph L., Sant, Karilyn E., Cho, Katherine H., Reed, Matthew S., Pohl, Jan, Hansen, Jason M., Harris, Craig
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2015
Onderwerpen:
Ethanol Disrupts Redox Balance During Organogenesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707201/
https://ncbi.nlm.nih.gov/pubmed/26185205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv145
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