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Poly-β amino ester-containing microparticles enhance the activity of nonviral genetic vaccines

Current nonviral genetic vaccine systems are less effective than viral vaccines, particularly in cancer systems where epitopes can be weakly immunogenic and antigen-presenting cell processing and presentation to T cells is down-regulated. A promising nonviral delivery method for genetic vaccines inv...

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Detalhes bibliográficos
Main Authors: Little, Steven R., Lynn, David M., Ge, Qing, Anderson, Daniel G., Puram, Sidharth V., Chen, Jianzhu, Eisen, Herman N., Langer, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470709/
https://ncbi.nlm.nih.gov/pubmed/15210954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403549101
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